|
|
cis,cis-delta11,23-C42:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta11,23-C42:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-196
|
|
|
|
cis,cis-delta19,37-3-hydroxy-C56:2-[acp] <=> trans-delta2-cis,cis-delta19,37-C56:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-440
|
|
|
|
(3R)-3-hydroxytetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] <=> (2E)-tetracos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + H2O
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN1G-517
|
|
|
|
cis,cis-delta11,23-3-hydroxyC42:2-[acp] <=> trans-delta2-cis,cis-delta11,23-C42:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-127
|
|
|
|
(3R)-3-hydroxyoctadecanoyl-[acp] + NADP+ <=> 3-oxooctadecanoyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN-9633
|
|
|
|
C86-trans-methoxy-mycolate-[pks13] + acceptor <=> 3-oxo-C86-trans-methoxy-mycolate-[pks13] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN1G-1528
|
|
|
|
ATP + trehalose-trans-keto-mono-mycolate + H2O <=> ADP + trehalose-trans-keto-mono-mycolate + phosphate + H+
|
7.5.2
|
–
|
| |
MetaCyc:
RXN1G-474
|
|
|
|
(5Z)-tetracos-5-enoyl-[acp] + NAD+ <=> (2E,5Z)-tetracosa-2,5-dienoyl-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-171
|
|
|
|
S-adenosyl-L-methionine + cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] <=> cis-delta19-37-methoxy-38-methyl-C57:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN-15340
|
|
|
|
stearoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxoicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21719
|
|
|
|
C78-alpha-mycolate-[pks13] + acceptor <=> 3-oxo-C78-alpha-mycolate-[pks13] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN1G-1486
|
|
|
|
S-adenosyl-L-methionine + cis-delta21-39-hydroxy-40-methyl-C59:1-[acp] <=> trans-delta20-39-hydroxy-40-methyl-C60:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-3660
|
|
|
|
cis-keto-C60-meroacyl-adenylate + 2-carboxycerotoyl-CoA + polyketide_synthase_PKS13 <=> 3-oxo-C86-cis-keto-mycolate-[pks13] + CO2 + CoA + AMP
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-296
|
|
|
|
C87-trans-keto-mycolate-[pks13] + acceptor <=> 3-oxo-C87-trans-keto-mycolate-[pks13] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN1G-1530
|
|
|
|
S-adenosyl-L-methionine + trans-delta18-37-hydroxy-20,38-dimethyl-C58:1-[acp] <=> trans-delta18-37-methoxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN-15342
|
|
|
|
ATP + trehalose-trans-methoxy-mono-mycolate + H2O <=> ADP + trehalose-trans-methoxy-mono-mycolate + phosphate + H+
|
7.5.2
|
–
|
| |
MetaCyc:
RXN1G-472
|
|
|
|
(3R,5Z)-3-hydroxytetracos-5-enoyl-[acp] <=> (2E,5Z)-tetracosa-2,5-dienoyl-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-27
|
|
|
|
(3R,7Z)-3-hydroxyhexacos-7-enoyl-[acp] + NADP+ <=> (7Z)-3-oxohexacos-7-enoyl-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-364
|
|
|
|
icosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-icos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21722
|
|
|
|
S-adenosyl-L-methionine + cis-delta21-39-oxo-40-methyl-C59:1-[acp] <=> cis-keto-C60-meroacyl-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1.79
cyclopropane-fatty-acyl-phospholipid synthase
|
–
|
| |
MetaCyc:
RXN1G-3641
|
|
|
|
cis,cis-delta9,27-3-hydroxyC46:2-[acp] <=> trans-delta2-cis,cis-delta9,27-C46:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-645
|
|
|
|
cis,cis-delta13,25-C44:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta13,25-C44:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-337
|
|
|
|
trehalose-cis-methoxy-mono-mycolate <=> trehalose-cis-methoxy-di-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1149
|
|
|
|
ATP + hexacosanoyl-CoA + HCO3- <=> 2-carboxycerotoyl-CoA + ADP + phosphate + H+
|
6.4.1.3
propionyl-CoA carboxylase
|
–
|
| |
MetaCyc:
RXN1G-4355
|
|
|
|
trehalose-cis-keto-mono-mycolate <=> trehalose-cis-keto-di-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1151
|
|
|
|
cis,cis-delta13,25-C44:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta15,27-3-oxo-C46:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-424
|
|
|
|
cis,cis-delta9,27-C46:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta11,29-3-oxo-C48:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-818
|
|
|
|
cis-keto-C60-meroacyl-[acp] + ATP + H2O <=> cis-keto-C60-meroacyl-adenylate + diphosphate + [acyl-carrier_protein]
|
6.2.1
|
–
|
| |
MetaCyc:
RXN1G-4142
|
|
|
|
cis-delta17-3-hydroxyC36:1-[acp] + NADP+ <=> cis-delta17-3-oxo-C36:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-881
|
|
|
|
cis,cis-delta5,17-3-hydroxyC36:2[acp] <=> trans-delta2-cis,cis-5,17-C36:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-464
|
|
|
|
cis,cis-delta9,27-C46:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta9,27-C46:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-686
|
|
|
|
cerotoyl-[acp_domain_within_a_fatty_acid_synthase] + CoA <=> hexacosanoyl-CoA + [acyl_carrier_protein]_domain_within_a_fatty_acid_synthase
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN1G-536
|
|
|
|
cis-delta11-3-hydroxyC30:1-[acp] + NADP+ <=> cis-delta11-3-oxo-C30:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-163
|
|
|
|
trans-delta2-cis-delta15-C34:2-[acp] <=> cis,cis-delta3,15-C34:2-[acp]
|
5.3.3.14
trans-2-decenoyl-[acyl-carrier protein] isomerase
|
–
|
| |
MetaCyc:
RXN1G-674
|
|
|
|
S-adenosyl-L-methionine + cis,cis-delta21,39-C58:2-[acp] + H2O <=> cis-delta21-39-hydroxy-40-methyl-C59:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-3613
|
|
|
|
cis,cis-delta17,35-3-hydroxyC54:2-[acp] + NADP+ <=> cis,cis-delta17,35-3-oxo-C54:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-184
|
|
|
|
(3R)-3-hydroxyoctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] <=> (2E)-octadec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + H2O
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-20770
|
|
|
|
cis,cis-delta19,31-3-hydroxyC50:2-[acp] + NADP+ <=> cis,cis-delta19,31-3-oxo-C50:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-951
|
|
|
|
palmitoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxooctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN3O-1803
|
|
|
|
cis,cis-delta17,29-C48:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta17,29-C48:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-820
|
|
|
|
cis-delta21-3-hydroxyC40:1-[acp] <=> trans-delta2-cis-delta21-C40:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-355
|
|
|
|
cis-delta9-3-hydroxyC28:1-[acp] + NADP+ <=> (9Z)-3-oxooctacos-9-enoyl-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-240
|
|
|
|
cis,cis-delta13,25-3-hydroxyC44:2-[acp] <=> trans-delta2-cis,cis-delta13,25-C44:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-294
|
|
|
|
S-adenosyl-L-methionine + cis,cis-delta19,31-C50:2-[acp] <=> C52-alpha-meroacyl-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-45
|
|
|
|
cis-delta19-3-hydroxyC38:1-[acp] <=> trans-delta2-cis-delta19-C38:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-1084
|
|
|
|
6-O-alpha-mycolyl-trehalose_6-phosphate + H2O <=> alpha,_alpha''-trehalose_6-alpha-mycolate + phosphate
|
3.1.3.12
trehalose-phosphatase
|
–
|
| |
MetaCyc:
RXN1G-1435
|
|
|
|
cis,cis-delta7,25-3-hydroxyC44:2-[acp] <=> trans-delta2-cis,cis-delta7,25-C44:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-425
|
|
|
|
cis-delta17-3-hydroxyC36:1-[acp] <=> trans-delta2-cis-delta17-C36:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-912
|
|
|
|
cis,cis-delta15,27-3-hydroxyC46:2-[acp] + NADP+ <=> cis,cis-delta15,27-3-oxo-C46:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-481
|
|
|
|
(3R,7Z)-3-hydroxyhexacos-7-enoyl-[acp] <=> (2E,7Z)-hexacosa-2,7-dienoyl-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-420
|
|
|
|
cis,cis-delta11,29-C48:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta13,31-3-oxo-C50:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-1015
|
|
|
|
mycobacterial_arabinogalactan + alpha,_alpha''-trehalose_6-alpha-mycolate <=> mycolyl-arabinogalactan-peptidoglycan_complex + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1633
|
|
|
|
cis,cis-delta17,29-3-hydroxyC48:2-[acp] <=> trans-delta2-cis,cis-delta17,29-C48:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-760
|
|
|
|
(7Z)-hexacos-7-enoyl-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> (9Z)-3-oxooctacos-9-enoyl-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-218
|
|
|
|
cis,cis-delta7,19-3-hydroxyC38:2-[acp] + NADP+ <=> cis,cis-delta7,19-3-oxo-C38:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-262
|
|
|
|
trans-methoxy-C60-meroacyl-[acp] + ATP + H2O <=> trans-methoxy-C60-meroacyl-adenylate + diphosphate + [acyl-carrier_protein]
|
6.2.1
|
–
|
| |
MetaCyc:
RXN1G-4141
|
|
|
|
C52-alpha-meroacyl-adenylate + 2-carboxycerotoyl-CoA + polyketide_synthase_PKS13 <=> 3-oxo-C78-alpha-mycolate-[pks13] + AMP + CoA + CO2
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-181
|
|
|
|
cis-delta17-C36:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta19-3-oxo-C38:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-1003
|
|
|
|
6-O-cis-keto-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + trehalose_phosphate <=> 6-O-cis-keto-mycolyl-trehalose_6-phosphate + D-mannopyranosyl-1-phosphoheptaprenol
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-810
|
|
|
|
cis,cis-delta15,33-C52:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta15,33-C52:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-1325
|
|
|
|
cis,cis-delta19-37-C56:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta19,37-C56:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-471
|
|
|
|
cis,cis-delta11,29-3-hydroxy_C48:2-[acp] <=> trans-delta2-cis,cis-delta11,29-C48:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-884
|
|
|
|
cis,cis-delta19,31-C50:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta19,31-C50:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-1057
|
|
|
|
cis,cis-delta21,39-3-hydroxyC58:2-[acp] <=> trans-delta2-cis,cis-delta21,39-C58:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-648
|
|
|
|
cis,cis-delta17,35-C54:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta17,35-C54:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-276
|
|
|
|
cis,cis-delta19,31-3-hydroxyC50:2-[acp] <=> trans-delta2-cis,cis-delta19,31-C50:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-1004
|
|
|
|
cis-delta9-C28:1-[acp] + NAD+ <=> trans-delta2-cis-delta9-C28:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-285
|
|
|
|
cis-delta15-C34:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta17-3-oxo-C36:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-840
|
|
|
|
cis,cis-delta21,39-C58:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta21,39-C58:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-679
|
|
|
|
lignoceroyl-[acp_domain_within_a_fatty_acid_synthase] + NAD+ <=> (2E)-tetracos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN1G-526
|
|
|
|
arachidoyl-[acp] + NAD+ <=> (2E)-icos-2-enoyl-[acp] + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
|
–
|
| |
MetaCyc:
RXN1G-395
|
|
|
|
lauroyl-CoA + malonyl-[acyl-carrier_protein] + H+ <=> CoA + 3-oxotetradecanoyl-[acyl-carrier_protein] + CO2
|
2.3.1.180
beta-ketoacyl-[acyl-carrier-protein] synthase III
2.3.1.ds
|
–
–
|
| |
BRENDA:
BS382199
MetaCyc:
RXN1G-460
|
|
|
|
cis,cis-delta7,25-C44:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta7,25-C44:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-468
|
|
|
|
cis,cis-delta17,35-3-hydroxyC54:2-[acp] <=> trans-delta2-cis,cis-delta17,35-C54:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-220
|
|
|
|
(3Z)-docos-3-enoyl-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> (5Z)-3-oxotetracos-5-enoyl-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-26
|
|
|
|
6-O-cis-keto-mycolyl-trehalose_6-phosphate + H2O <=> trehalose-cis-keto-mono-mycolate + phosphate
|
3.1.3.12
trehalose-phosphatase
|
–
|
| |
MetaCyc:
RXN1G-1438
|
|
|
|
cis,cis-delta11,23-C42:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta13,25-3-oxo-C44:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-32
|
|
|
|
cis-delta9-C28:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta11-3-oxo-C30:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-138
|
|
|
|
(3R)-3-hydroxyicosanoyl-[acp] <=> (2E)-icos-2-enoyl-[acp] + H2O
|
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
|
| |
MetaCyc:
RXN1G-320
|
|
|
|
(3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN-9540
|
|
|
|
cis,cis-delta7,19-3-hydroxyC38:2-[acp] <=> trans-delta2-cis-cis-delta7-19-C38:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-308
|
|
|
|
cis-delta13-3-hydroxyC32:1-[acp] + NADP+ <=> cis-delta13-3-oxo-C32:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-260
|
|
|
|
cis,cis-delta5,23-3-hydroxyC42:2-[acp] <=> trans-delta2-cis,cis-delta5,23-C42:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-214
|
|
|
|
(3R)-3-hydroxyhexadecanoyl-[acp] <=> H2O + trans-Hexadec-2-enoyl-[acp]
|
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
|
| |
MetaCyc:
4.2.1.61-RXN
|
|
|
|
6-O-trans-methoxy-mycolyl-trehalose_6-phosphate + H2O <=> trehalose-trans-methoxy-mono-mycolate + phosphate
|
3.1.3.12
trehalose-phosphatase
|
–
|
| |
MetaCyc:
RXN1G-1437
|
|
|
|
docosanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxotetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN1G-499
|
|
|
|
cis,cis-delta5,23-3-hydroxyC42:2-[acp] + NADP+ <=> cis,cis-delta5,23-3-oxo-C42:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-182
|
|
|
|
cis-delta15-C34:1-[acp] + NAD+ <=> trans-delta2-cis-delta15-C34:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-396
|
|
|
|
stearoyl-[acyl-carrier_protein] + NAD+ <=> (2E)-Octadecenoyl-[acp] + NADH + H+
|
1.3.1
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1
|
–
–
–
|
| |
KEGG:
R07765
MetaCyc:
RXN-9635
|
|
|
|
cis,cis-delta3,15-C34:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta5,17-3-oxo-C36:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-202
|
|
|
|
cis-delta15-3-hydroxyC34:1-[acp] <=> trans-delta2-cis-delta15-C34:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-377
|
|
|
|
cis-delta17-C36:1-[acp] + NAD+ <=> trans-delta2-cis-delta17-C36:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-962
|
|
|
|
(3R)-3-hydroxyoctadecanoyl-[acp] <=> (2E)-Octadecenoyl-[acp] + H2O
|
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
|
| |
MetaCyc:
RXN-9634
|
|
|
|
cis,cis-delta9,21-C40:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta11,23-3-oxo-C42:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-580
|
|
|
|
6-O-trans-keto-mycolyl-trehalose_6-phosphate + H2O <=> trehalose-trans-keto-mono-mycolate + phosphate
|
3.1.3.12
trehalose-phosphatase
|
–
|
| |
MetaCyc:
RXN1G-1439
|
|
|
|
cis-methoxy-C59-meroacyl-adenylate + 2-carboxycerotoyl-CoA + polyketide_synthase_PKS13 <=> 3-oxo-C85-cis-methoxy-mycolate-[pks13] + CoA + AMP + CO2
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-98
|
|
|
|
cis,cis-delta15,27-C46:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta15,27-C46:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-607
|
|
|
|
(3R)-3-hydroxydocosanoyl-[acp_domain_within_a_fatty_acid_synthase] <=> (2E)-docos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + H2O
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21725
|
|
|
|
cis,cis-delta5,17-C36:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta7,19-3-oxo-C38:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-89
|
|
|
|
(3R)-3-hydroxyoctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxooctadecanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-20769
|
|
|
|
trans-delta20-39-hydroxy-40-methyl-C60:1-[acp] + acceptor <=> trans-delta20-39-oxo-40-methyl-C60:1-[acp] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN-15339
|
|
|
|
cis,cis-delta15,27-3-hydroxyC46:2-[acp] <=> trans-delta2-cis,cis-delta15,27-C46:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-554
|
|
|
|
ATP + alpha,_alpha''-trehalose_6-alpha-mycolate + H2O <=> ADP + alpha,_alpha''-trehalose_6-alpha-mycolate + phosphate + H+
|
7.5.2
|
–
|
| |
MetaCyc:
RXN1G-137
|
|
|
|
(2E)-docos-2-enoyl-[acp] <=> (3Z)-docos-3-enoyl-[acp]
|
5.3.3.14
trans-2-decenoyl-[acyl-carrier protein] isomerase
|
–
|
| |
MetaCyc:
RXN1G-30
|
|
|
|
(3R)-3-hydroxyicosanoyl-[acp] + NADP+ <=> 3-oxo-arachidoyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-349
|
|
|
|
cis-delta19-C38:1-[acp] + NAD+ <=> trans-delta2-cis-delta19-C38:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-1130
|
|
|
|
(3R)-3-hydroxyhexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxohexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-10060
|
|
|
|
cis,cis-delta13,31-C50:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta13,31-C50:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-1117
|
|
|
|
S-adenosyl-L-methionine + trans-delta18-37-methoxy-20,38-dimethyl-C58:1-[acp] <=> trans-methoxy-C60-meroacyl-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-3256
|
|
|
|
cis,cis-delta9,21-3-hydroxyC40:2-[acp] <=> trans-delta2-cis,cis-9,21-C40:3-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-309
|
|
|
|
cis,cis-delta13,31-3-hydroxy_C50:2-[acp] <=> trans-delta2-cis,cis-delta13,31-C50:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-1081
|
|
|
|
cis-delta13-C32:1-[acp] + NAD+ <=> trans-delta2-cis-delta13-C32:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-299
|
|
|
|
6-O-cis-methoxy-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + trehalose_phosphate <=> 6-O-cis-methoxy-mycolyl-trehalose_6-phosphate + D-mannopyranosyl-1-phosphoheptaprenol
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-808
|
|
|
|
6-O-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + trehalose_phosphate <=> 6-O-alpha-mycolyl-trehalose_6-phosphate + D-mannopyranosyl-1-phosphoheptaprenol
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-807
|
|
|
|
(7Z)-hexacos-7-enoyl-[acp] + NAD+ <=> (2E,7Z)-hexacosa-2,7-dienoyl-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-37
|
|
|
|
S-adenosyl-L-methionine + cis,cis-delta19-37-C56:2-[acp] + H2O <=> cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-2527
|
|
|
|
cis,cis-delta3,21-C40:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta5,23-3-oxo-C42:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-79
|
|
|
|
cis,cis-delta15,33-3-hydroxy_C52:2-[acp] <=> trans-delta2-cis,cis-delta15,33-C52:3-[acp] + H2O
|
4.2.1.M2
|
–
|
| |
MetaCyc:
RXN1G-1278
|
|
|
|
C52-alpha-meroacyl-[acp] + ATP + H2O <=> C52-alpha-meroacyl-adenylate + diphosphate + [acyl-carrier_protein]
|
6.2.1
|
–
|
| |
MetaCyc:
RXN1G-3993
|
|
|
|
cis,cis-delta11,29-3-hydroxy_C48:2-[acp] + NADP+ <=> cis,cis-delta11,29-3-oxo-C48:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-853
|
|
|
|
cis,cis-delta15,33-3-hydroxy_C52:2-[acp] + NADP+ <=> cis,cis-delta15,33-3-oxo-C52:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-1247
|
|
|
|
cis,cis-delta17,29-C48:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta19,31-3-oxo-C50:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-883
|
|
|
|
cis,cis-delta15,27-C46:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta17,29-3-oxo-C48:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-660
|
|
|
|
cis,cis-delta5,17-C36:2-[acp] + NAD+ <=> trans-delta2-cis,cis-5,17-C36:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-193
|
|
|
|
lignoceroyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxohexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CoA + CO2
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-10059
|
|
|
|
cis-delta21-3-hydroxyC40:1-[acp] + NADP+ <=> cis-delta21-3-oxo-C40:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-287
|
|
|
|
trans-delta2-cis-delta21-C40:2-[acp] <=> cis,cis-delta3,21-C40:2-[acp]
|
5.3.3.14
trans-2-decenoyl-[acyl-carrier protein] isomerase
|
–
|
| |
MetaCyc:
RXN1G-53
|
|
|
|
S-adenosyl-L-methionine + cis-delta19-37-methoxy-38-methyl-C57:1-[acp] <=> cis-methoxy-C59-meroacyl-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1.79
cyclopropane-fatty-acyl-phospholipid synthase
|
–
|
| |
MetaCyc:
RXN1G-2544
|
|
|
|
(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
|
| |
KEGG:
R04566
MetaCyc:
RXN-9536
|
|
|
|
S-adenosyl-L-methionine + cis-delta19-37-hydroxy-38-methyl-C57:1-[acp] <=> trans-delta18-37-hydroxy-20,38-dimethyl-C58:1-[acp] + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
| |
MetaCyc:
RXN1G-3232
|
|
|
|
mycobacterial_arabinogalactan + trehalose-cis-methoxy-mono-mycolate <=> arabinogalactan-cis-methoxy-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1634
|
|
|
|
cis,cis-delta13,31-C50:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta15,33-3-oxo-C52:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-1212
|
|
|
|
(3R)-3-hydroxytetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxotetracosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN1G-508
|
|
|
|
(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O
|
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
4.2.1
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
–
–
–
–
|
| |
KEGG:
R04568
MetaCyc:
RXN-9537
|
|
|
|
alpha,_alpha''-trehalose_6-alpha-mycolate <=> alpha,_alpha''-trehalose_6,6''-bismycolate + trehalose
|
2.3.1.122
trehalose O-mycolyltransferase
|
–
|
| |
MetaCyc:
RXN1G-874
|
|
|
|
(3R)-3-hydroxydocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxodocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21724
|
|
|
|
cis,cis-delta7,25-C44:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta9,27-3-oxo-C46:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-557
|
|
|
|
mycobacterial_arabinogalactan + trehalose-trans-methoxy-mono-mycolate <=> arabinogalactan-trans-methoxy-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1635
|
|
|
|
(3R)-3-hydroxyicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> 3-oxoicosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21720
|
|
|
|
malonyl-[acyl-carrier_protein] + arachidoyl-[acp] + H+ <=> 3-oxodocosanoyl-[acp] + CO2 + [acyl-carrier_protein]
|
2.3.1.41
beta-ketoacyl-[acyl-carrier-protein] synthase I
|
–
|
| |
MetaCyc:
RXN1G-445
|
|
|
|
cis,cis-delta9,21-C40:2-[acp] + NAD+ <=> trans-delta2-cis,cis-9,21-C40:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-509
|
|
|
|
(3R)-3-hydroxydocosanoyl-[acp] <=> (2E)-docos-2-enoyl-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-363
|
|
|
|
C78-alpha-mycolate-[pks13] + D-mannopyranosyl-1-phosphoheptaprenol <=> 6-O-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + polyketide_synthase_PKS13
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-288
|
|
|
|
cis,cis-delta9,27-3-hydroxyC46:2-[acp] + NADP+ <=> cis,cis-delta9,27-3-oxo-C46:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-613
|
|
|
|
cis-delta11-C30:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta13-3-oxo-C32:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-236
|
|
|
|
6-O-cis-methoxy-mycolyl-trehalose_6-phosphate + H2O <=> trehalose-cis-methoxy-mono-mycolate + phosphate
|
3.1.3.12
trehalose-phosphatase
|
–
|
| |
MetaCyc:
RXN1G-1436
|
|
|
|
cis-delta19-C38:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta21-3-oxo-C40:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-132
|
|
|
|
C85-cis-methoxy-mycolate-[pks13] + acceptor <=> 3-oxo-C85-cis-methoxy-mycolate-[pks13] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN1G-1527
|
|
|
|
icosanoyl-[acp_domain_within_a_fatty_acid_synthase] + malonyl-CoA + H+ <=> 3-oxodocosanoyl-[acp_domain_within_a_fatty_acid_synthase] + CO2 + CoA
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21723
|
|
|
|
cis-delta11-C30:1-[acp] + NAD+ <=> trans-delta2-cis-delta11-C30:2-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-210
|
|
|
|
cis,cis-delta17,35-C54:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta19,37-3-oxo-C56:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-374
|
|
|
|
cis-methoxy-C59-meroacyl-[acp] + ATP + H2O <=> cis-methoxy-C59-meroacyl-adenylate + diphosphate + [acyl-carrier_protein]
|
6.2.1
|
–
|
| |
MetaCyc:
RXN1G-4140
|
|
|
|
tetradecanoyl-[acyl-carrier_protein] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1
|
–
–
|
| |
KEGG:
R04966
MetaCyc:
RXN-9662
|
|
|
|
cis,cis-delta19,37-3-hydroxy-C56:2-[acp] + NADP+ <=> cis,cis-delta19,37-3-oxo-C56:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-409
|
|
|
|
cis,cis-delta7,19-C38:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta9,21-3-oxo-C40:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-172
|
|
|
|
cis,cis-delta19-37-C56:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta21,39-3-oxo-C58:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-582
|
|
|
|
C85-cis-methoxy-mycolate-[pks13] + D-mannopyranosyl-1-phosphoheptaprenol <=> 6-O-cis-methoxy-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + polyketide_synthase_PKS13
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-289
|
|
|
|
cis,cis-delta5,23-C42:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta5,23-C42:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-248
|
|
|
|
cis,cis-delta5,17-3-hydroxyC36:2[acp] + NADP+ <=> cis,cis-delta5,17-3-oxo-C36:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-408
|
|
|
|
trans-methoxy-C60-meroacyl-adenylate + 2-carboxycerotoyl-CoA + polyketide_synthase_PKS13 <=> 3-oxo-C86-trans-methoxy-mycolate-[pks13] + CO2 + CoA + AMP
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-295
|
|
|
|
cis,cis-delta17,29-3-hydroxyC48:2-[acp] + NADP+ <=> cis,cis-delta17,29-3-oxo-C48:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-717
|
|
|
|
C86-cis-keto-mycolate-[pks13] + acceptor <=> 3-oxo-C86-cis-keto-mycolate-[pks13] + reduced_acceptor
|
1.1
|
–
|
| |
MetaCyc:
RXN1G-1529
|
|
|
|
cis,cis-delta15,33-C52:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta17,35-3-oxo-C54:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-94
|
|
|
|
cis-delta13-C32:1-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis-delta15-3-oxo-C34:1-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-324
|
|
|
|
(3R)-3-hydroxydocosanoyl-[acp] + NADP+ <=> 3-oxodocosanoyl-[acp] + NADPH + H+
|
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-469
|
|
|
|
cerotoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-hexacos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-10062
|
|
|
|
(5Z)-tetracos-5-enoyl-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> (7Z)-3-oxohexacos-7-enoyl-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.293
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I
|
–
|
| |
MetaCyc:
RXN1G-306
|
|
|
|
cis-delta11-3-hydroxyC30:1-[acp] <=> trans-delta2-cis-delta11-C30:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-188
|
|
|
|
docosanoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-docos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21726
|
|
|
|
(3R)-3-hydroxyhexacosanoyl-[acp_domain_within_a_fatty_acid_synthase] <=> (2E)-hexacos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + H2O
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-10061
|
|
|
|
trans-keto-C61-meroacyl-[acp] + ATP + H2O <=> trans-keto-C61-meroacyl-adenylate + diphosphate + [acyl-carrier_protein]
|
6.2.1
|
–
|
| |
MetaCyc:
RXN1G-4143
|
|
|
|
trehalose-trans-keto-mono-mycolate <=> trehalose-trans-keto-di-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1152
|
|
|
|
mycobacterial_arabinogalactan + trehalose-trans-keto-mono-mycolate <=> arabinogalactan-trans-keto-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1637
|
|
|
|
cis-delta19-3-hydroxyC38:1-[acp] + NADP+ <=> cis-delta19-3-oxo-C38:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-1053
|
|
|
|
palmitoyl-[acyl-carrier_protein] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1
|
–
–
|
| |
KEGG:
R04969
MetaCyc:
RXN-9663
|
|
|
|
cis,cis-delta5,23-C42:2-[acp] + malonyl-[acyl-carrier_protein] + H+ <=> cis,cis-delta7,25-3-oxo-C44:2-[acp] + [acyl-carrier_protein] + CO2
|
2.3.1.294
meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II
|
–
|
| |
MetaCyc:
RXN1G-334
|
|
|
|
cis-delta15-3-hydroxyC34:1-[acp] + NADP+ <=> cis-delta15-3-oxo-C34:1-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-358
|
|
|
|
stearoyl-[acp_domain_within_a_fatty_acid_synthase] + NADP+ <=> (2E)-octadec-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + NADPH + H+
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN3O-5293
|
|
|
|
C87-trans-keto-mycolate-[pks13] + D-mannopyranosyl-1-phosphoheptaprenol <=> 6-O-trans-keto-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + polyketide_synthase_PKS13
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-292
|
|
|
|
palmitoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxooctadecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein]
|
2.3.1
2.3.1.179
beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.199
very-long-chain 3-oxoacyl-CoA synthase
2.3.1.41
beta-ketoacyl-[acyl-carrier-protein] synthase I
|
–
–
–
–
|
| |
BRENDA:
BS320874;
BS377477
KEGG:
R07762
MetaCyc:
RXN-9632
SABIO-RK:
11307
|
|
|
|
cis-delta13-3-hydroxyC32:1-[acp] <=> trans-delta2-cis-delta13-C32:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-279
|
|
|
|
cis,cis-delta9,21-3-hydroxyC40:2-[acp] + NADP+ <=> cis,cis-delta9,21-3-oxo-C40:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-252
|
|
|
|
mycobacterial_arabinogalactan + trehalose-cis-keto-mono-mycolate <=> arabinogalactan-cis-keto-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1636
|
|
|
|
cis,cis-delta11,23-3-hydroxyC42:2-[acp] + NADP+ <=> cis,cis-delta11,23-3-oxo-C42:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-637
|
|
|
|
ATP + trehalose-cis-methoxy-mono-mycolate + H2O <=> ADP + trehalose-cis-methoxy-mono-mycolate + phosphate + H+
|
7.5.2
|
–
|
| |
MetaCyc:
RXN1G-470
|
|
|
|
cis-delta9-3-hydroxyC28:1-[acp] <=> trans-delta2-cis-delta9-C28:2-[acp] + H2O
|
4.2.1.M1
|
–
|
| |
MetaCyc:
RXN1G-266
|
|
|
|
cis,cis-delta11,29-C48:2-[acp] + NAD+ <=> trans-delta2-cis,cis-delta11,29-C48:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-915
|
|
|
|
C86-cis-keto-mycolate-[pks13] + D-mannopyranosyl-1-phosphoheptaprenol <=> 6-O-cis-keto-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + polyketide_synthase_PKS13
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-291
|
|
|
|
(3R,5Z)-3-hydroxytetracos-5-enoyl-[acp] + NADP+ <=> (5Z)-3-oxotetracos-5-enoyl-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-72
|
|
|
|
cis-delta21-39-hydroxy-40-methyl-C59:1-[acp] + acceptor <=> cis-delta21-39-oxo-40-methyl-C59:1-[acp] + reduced_acceptor
|
1.1.1
|
–
|
| |
MetaCyc:
RXN-15338
|
|
|
|
6-O-trans-keto-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + trehalose_phosphate <=> 6-O-trans-keto-mycolyl-trehalose_6-phosphate + D-mannopyranosyl-1-phosphoheptaprenol
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-811
|
|
|
|
trans-delta20-39-oxo-40-methyl-C60:1-[acp] <=> trans-keto-C61-meroacyl-[acp]
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-3667
|
|
|
|
cis,cis-delta13,31-3-hydroxy_C50:2-[acp] + NADP+ <=> cis,cis-delta13,31-3-oxo-C50:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-1050
|
|
|
|
trans-keto-C61-meroacyl-adenylate + 2-carboxycerotoyl-CoA + polyketide_synthase_PKS13 <=> 3-oxo-C87-trans-keto-mycolate-[pks13] + CO2 + CoA + AMP
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-297
|
|
|
|
cis,cis-delta13,25-3-hydroxyC44:2-[acp] + NADP+ <=> cis,cis-delta13,25-3-oxo-C44:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-203
|
|
|
|
(3R)-3-hydroxyicosanoyl-[acp_domain_within_a_fatty_acid_synthase] <=> (2E)-icos-2-enoyl-[acp_domain_within_a_fatty_acid_synthase] + H2O
|
2.3.1.86
fatty-acyl-CoA synthase system
|
–
|
| |
MetaCyc:
RXN-21721
|
|
|
|
C86-trans-methoxy-mycolate-[pks13] + D-mannopyranosyl-1-phosphoheptaprenol <=> 6-O-trans-methoxy-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + polyketide_synthase_PKS13
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-290
|
|
|
|
cis,cis-delta21,39-3-hydroxyC58:2-[acp] + NADP+ <=> cis,cis-delta21,39-3-oxo-C58:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-617
|
|
|
|
ATP + trehalose-cis-keto-mono-mycolate + H2O <=> ADP + trehalose-cis-keto-mono-mycolate + phosphate + H+
|
7.5.2
|
–
|
| |
MetaCyc:
RXN1G-473
|
|
|
|
cis,cis-delta7,19-C38:2-[acp] + NAD+ <=> trans-delta2-cis-cis-delta7-19-C38:3-[acp] + NADH + H+
|
1.3.1.118
meromycolic acid enoyl-[acyl-carrier-protein] reductase
|
–
|
| |
MetaCyc:
RXN1G-339
|
|
|
|
trehalose-trans-methoxy-mono-mycolate <=> trehalose-trans-methoxy-di-mycolate + trehalose
|
2.3.1
|
–
|
| |
MetaCyc:
RXN1G-1150
|
|
|
|
malonyl-[acyl-carrier_protein] + stearoyl-[acyl-carrier_protein] + H+ <=> 3-oxo-arachidoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein]
|
2.3.1.41
beta-ketoacyl-[acyl-carrier-protein] synthase I
|
–
|
| |
MetaCyc:
RXN1G-368
|
|
|
|
cis,cis-delta7,25-3-hydroxyC44:2-[acp] + NADP+ <=> cis,cis-delta7,25-3-oxo-C44:2-[acp] + NADPH + H+
|
1.1.1.M9
|
–
|
| |
MetaCyc:
RXN1G-384
|
|
|
|
tetradecanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein]
|
2.3.1
2.3.1.179
beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41
beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
|
| |
BRENDA:
BS320873
KEGG:
R04968
MetaCyc:
RXN-9539
SABIO-RK:
4606
|
|
|
|
6-O-trans-methoxy-mycolyl-beta-D-mannopyranosyl-1-phosphoheptaprenol + trehalose_phosphate <=> 6-O-trans-methoxy-mycolyl-trehalose_6-phosphate + D-mannopyranosyl-1-phosphoheptaprenol
|
not assigned
|
–
|
| |
MetaCyc:
RXN1G-809
|
|
